TTS 2026 Program

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Sunday, September 20, 2026

Cockle Bay 1
Post-Graduate Course - Clinical Program
Post-Graduate Course

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Xeno – evolution & current state
Richard N. Pierson (US)
Darling Harbour
Plenary Session 1
Plenary Session
Chairs Medhat Askar (US) · John J. Fung (US)

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Early clinical experience with gene-edited porcine kidney xenotransplantation in four living human recipients
Leonardo Riella (US)

Monday, September 21, 2026

Darling Harbour
Plenary Session 2
Plenary Session

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Clinical xenotransplantation: Experience to date
Tatsuo Kawai (US)
Xenozoonosis, no worries!
Anoma Nellore (US)
The ethics of new technology in xenotransplantation
Luz Padilla (US)
Room C4.6
Patient-centered outcomes and psychosocial determinants in kidney transplantation: From digital health to life course impacts
Abstract Session Clinical Research/trials
Chairs Audrey Au Yong (GB) · Adem Safak (TR)

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Identifying research priorities in kidney transplantation: a priority setting partnership with patients, caregivers and healthcare professionals.
Nicole Jane Scholes-Robertson (AU)
Parkside 1&2
Hansa BioPharma Corporate Lunch Symposium on Transplanting the untransplantable – Idefirix® (imlifidase), a breakthrough innovation for highly sensitised kidney transplantation
Industry Symposium
Chair Steve Chadban (AU)

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Short and long-term outcomes of imlifidase-enabled transplantation: ConfIdeS and beyond
Robert A. Montgomery (US)
The Gallery
Lunch and Learn Roundtable
Experts/Mentors

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Infectious disease surveillance and management in clinical xenotransplantation
Jay Fishman (US)
Cockle Bay 2
Omics in transplantation 1
Abstract Session Basic and Translational Science
Chairs Ana Konvalinka (CA) · Carol Pollock (AU)

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Lipid-associated macrophage polarization and APOE–SDC2 signaling underlies chronic xenograft fibrosis
Minhee Seong (KR)
Hall 1-2
Poster Session 1
Posters

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Short-course anti-CD154 induction followed by tacrolimus maintenance sustains pig-to-cynomolgus kidney xenograft function
Sun Ae Hwang (KR)
Mycophenolic acid suppresses human monocyte-macrophage cytotoxicity against swine endothelial cells through guanosine depletion
Yusuke Yanagino (JP)
Human NK Cell Activation by Porcine cells Compared to Allogeneic Human Cells
Eunjee Oh (KR)
Novel RORγ inverse agonists: Dual-action therapy for promoting graft tolerance while inhibiting tumor growth
Jean Tchervenkov (CA)

Tuesday, September 22, 2026

Cockle Bay 2
Immunosuppression: Experimental and clinical
Abstract Session Basic and Translational Science
Chairs Jaeseok Yang (KR) · Raman Venkataramanan (US)

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Pre‑IND Evaluation of Orthotopic Cardiac Xenotransplantation Using Ten‑Gene‑Edited Porcine Donor Hearts with a Clinically Relevant Immunosuppressive Regimen in Non‑Human Primates
Muhammad Mohiuddin (US)
Room C4.4
The journey to clinical xenotransplantation
Concurrent Xenotransplantation
Chairs Leonardo Riella (US) · Evelyn Salvaris (AU)

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2025 Carl-Gustav Groth Xeno Prize for the paper on "Desensitization with Proteasome Inhibition and Costimulation Blockade Modulates the Xenoreactive Humoral Response in Nonhuman Primate Xenotransplantation"
Brendan P. Lovasik (US)
Development of the gene edited pigs to get us to the clinic
Peter Cowan (AU)
Avoiding dysregulation of the complement and coagulation-anticoagulation systems?
Richard N. Pierson (US)
The road to regulatory approval for clinical transplantation
Muhammad Mohiuddin (US)
Room C3.4-C3.5
Immunoregulation: Cell signalling 2
Abstract Session Basic and Translational Science
Chairs Kate Gartlan (AU) · Lucy Sullivan (AU)

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Investigation of immune responses to SLA-derived antigens presented on HLA class II
Ken Kawada (JP)
Room C4.1
Overcoming immune barriers in xenotransplantation: From innate recognition to gene-edited graft compatibility
Abstract Session Xenotransplantation
Chairs Richard N. Pierson (US) · Peter Cowan (AU)

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Loss of Neu5Gc in donor erythrocytes unlocks species-specific innate checkpoints governing macrophage recognition in xenotransplantation
Wang Yi (CN)
Normothermic Machine Perfusion of Human Kidneys Using Triple-Knockout Pig Red Blood Cells
Shuangjin Yu (CN)
First Large-Cohort Study Profiling the Baseline Immunological Status for Xenotransplantation in Liver Transplant Candidates: Implications for Safe Bridging from Gene-Edited Pigs
Liaoran Wang (CN)
Antibody responses against swine leukocyte antigens contribute to early rejection after pig-to-monkey kidney xenotransplantation
Hao Feng (CN)
Preformed and De Novo Xenoreactive IgM Antibodies Contribute to Early Xenograft Loss in Pig-to-Monkey Kidney Xenotransplantation
Man Zhang (CN)
Sequential Allotransplantation After Failure of Pig-to-Rhesus monkey Kidney Xenotransplantation: A Case Report
Man Zhang (CN)
Flow cytometry immune profiling provides early detection of rejection of islet xenotransplants
Thanh Le (AU)
HLA E CD94 NKG2A pathway confers superior NK cell resistance compared to extensive multitransgenic modifications in porcine endothelial cells
Jonathan Schulz (DE)
Endothelial PlexinB2 suppresses human neutrophil activation in a humanized xenotransplantation model
Shuji Miyagawa (JP)
Hall 1-2
Poster Session 2
Posters

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Development of knock-in porcine cell lines expressing human immune genes under endogenous promoters for xenotransplantation
Dong Eon Kim (KR)
Fabrication and Functional Validation of Parathyroid Organoids for Xenotransplantation in Non-Human Primates: Therapeutic approaches to hypoparathyroidism
Eun Yeol Yang (KR)
CD40–CD154 costimulation blockade enables safe repeated xenotransfusion of genetically engineered porcine red blood cells in nonhuman primates
Hee Jung Kang (KR)
How the UAE’s Legal Framework is Driving a Model Organ Donation and Transplantation System in the Arab World
Maria Gomez (AE)

Wednesday, September 23, 2026

Room C3.4-C3.5
Insights into old and new therapeutics 2
Abstract Session Basic and Translational Science
Chairs Philip O'Connell (AU) · Zhejia Tian (DE)

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Tacrolimus-resistant regulatory T cells in allotransplantation
Naeem Abdul Ghafoor (GB)
Room C4.7
Advancing islet and stem cell transplantation: Immune modulation, bioengineering, and graft survival
Abstract Session Pancreas and Islet
Chairs Hanne Scholz (NO) · Gregory S. Korbutt (CA)

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The potential of Macaca fuscata, as a recipient model for porcine islet xenotransplantation
Naoaki Sakata (JP)
Engineering Pancreatic Islet Organoids with a Hierarchical Vascular Network
Jialin Cui (JP)
Room C4.11
Vascularized tissue engineering and organ-on-chip platforms for transplantation and organ replacement
Abstract Session Regenerative Medicine/Cell Tx
Chairs Maria Siemionow (US) · Subramania Iyer (IN)

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Functional Restoration of Apico-basal Polarity and Vascularization in Liver Organoids: A Highly Physiological Unit for Organ Replacement
Mengyu Gao (CN)
Cockle Bay 1
Clinical Xenotransplantation has Arrived!
SOTA/Thematic Session Xenotransplantation
Chairs Wayne J. Hawthorne (AU) · Robert A. Montgomery (US)

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Understanding optimal genetic modification
Peter Cowan (AU)
Experience and immunosuppression for clinical xenotransplantation
Muhammad Mohiuddin (US)
Special challenges of lung xenotransplantation
Richard N. Pierson (US)
Clinical xenotransplantation: A new era through the eyes of patients and families
Macey L. Levan (US)
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