Infectious disease surveillance and management in clinical xenotransplantation
Jay Fishman (US)
Professor of Medicine · Transplant Infectious Disease · Mass General Hospital - Harvard Medical School · Boston
Jay A. Fishman, M.D. is Professor of Medicine at Harvard Medical School (HMS), Director of the Transplant Infectious Diseases and Compromised Host Program at Massachusetts General Hospital (MGH), and Associate Director of the MGH Transplant Center. Dr. Fishman received his MD from Johns Hopkins University School of Medicine, internal medicine training and Infectious Disease Fellowship at MGH, and postdoctoral Fellowships in Molecular Biology and Genetics at MGH and HMS. He completed the General Management Program at Harvard Business School. His studies defined the use of ganciclovir for CMV infection in transplantation. His clinical and basic research is focused on molecular studies of opportunistic pathogens in immunocompromised hosts in animal models and humans. His lab cloned and sequenced the porcine endogenous retrovirus (PERV) from swine and performed the first studies of porcine cytomegalovirus (PCMV) in pigs and baboon transplant recipients. His mechanistic studies demonstrated the role of human CMV infection in incapacitating monocyte phagocytosis of fungal pathogens while inciting allograft rejection and graft-versus-host disease; these innate immune mechanisms explain the “indirect effects” of CMV in transplantation. Dr. Fishman has a special interest in education and mentorship having established the first worldwide Transplant and Immunocompromised Host Program at MGH. He is Fellow of the American College of Physicians, American Society of Transplantation, and Infectious Disease Society of America. He is Past-President of the American Society of Transplantation, President of the International Xenotransplantation Association and Councilor of the Transplantation Society. He has received career achievement awards from AST and TTS.